Platelet-dependent vascular occlusion

Cover of: Platelet-dependent vascular occlusion |

Published by New York Academy of Sciences in New York .

Written in English

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  • Atherosclerosis -- Pathophysiology -- Congresses,
  • Thrombosis -- Congresses,
  • Blood platelet disorders -- Congresses,
  • Blood platelets -- Congresses,
  • Vascular Diseases -- etiology -- congresses,
  • Platelet Activation -- physiology -- congresses

Edition Notes

Book details

Statementedited by Garret A. FitzGerald, Lisa K. Jennings, and Carlo Patrono.
SeriesAnnals of the New York Academy of Sciences,, v. 714
ContributionsFitzGerald, G. A., Jennings, Lisa K., Patrono, Carlo, 1944-, New York Academy of Sciences., International Meeting on Platelets and Vascular Occlusion (3rd : 1993 : Santa Fe, N.M.)
LC ClassificationsQ11 .N5 vol. 714, RC692 .N5 vol. 714
The Physical Object
Paginationvii, 328 p. :
Number of Pages328
ID Numbers
Open LibraryOL1083635M
ISBN 100897668456, 0897668464
LC Control Number94007321

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Platelet-Dependent Vascular Occlusion: (Annals of the New York Academy of Sciences) [New York Academy of Sciences, International Meeting on Platelets and Vascular Occlusion (3rd: Santa Fe, N. M.), Fitzgerald, G. A., Jennings, Lisa K., Patrono, Carlo] on *FREE* shipping on qualifying offers.

Platelet-Dependent Vascular Occlusion: (Annals of the New York Author: New York Academy of Sciences, N. M.) International Meeting on Platelets and Vascular Occlusion (3rd: Santa Fe. Activated platelets adhere to leukocytes, sickle erythrocytes and endothelium to promote vaso-occlusion and/or vascular thrombosis.

The knowledge of the platelet-dependent pathophysiology has led to the development of new therapies for SCD, by targeting different processes leading.

The present invention relates generally to methods and compositions for targeting and delivering solid-phase platelet-dependent vascular occlusion agents. In particular, particles or coils or stents coated with platelet binding agents are directed to target vasculature, such as the vasculature of solid tumor masses or AV-malformations or.

Platelet-dependent vascular occlusion. Proceedings of the 3rd International Meeting of Platelets and Vascular Occlusion. Santa Fe, New Mexico, June The present invention relates generally to methods Platelet-dependent vascular occlusion book compositions for targeting, delivering, and activating platelet-dependent vascular occlusion agents.

In particular, fusion proteins carrying platelet binding agents are targeted to hyperplastic cells or tissues, such as the vasculature of solid tumor masses; the platelet binding agent then.

2 days ago  In these patients, parent artery sacrifice and bypass revascularization for aneurysm occlusion is an option. There are three strategies for parent artery sacrifice: trapping, complete occlusion of the inflow and outflow segment, proximal occlusion of the inflow vessel, and distal occlusion of the outflow vessel(s).

Occlusive peripheral arterial disease is blockage or narrowing of an artery in the legs (or rarely the arms), usually due to atherosclerosis and resulting in decreased blood flow.

Occlusive peripheral arterial disease is common among older people because it often results from atherosclerosis (plaque. 2 days ago  ALISO VIEJO, Calif., Dec. 16, /PRNewswire/ -- Okami Medical Inc., a medical device company, today announced the expansion of its LOBO ™ Vascular Occlusion.

Vascular occlusion, also known as vascular thrombosis or blocked artery, is characterized by a blocked vein, normally due to the presence of a blood occlusion is sometimes the result of a sudden blockage, which can cause serious symptoms and may even result in.

The present invention relates generally to methods and compositions for targeting, delivering, and activating platelet-dependent vascular occlusion agents.

In particular, antibodies carrying platelet binding agents are targeted to hyperplastic cells or tissues, such as the vasculature of solid tumor masses; the platelet binding agent then binds.

Vascular occlusion and thrombosis book. By Sunil R. Lakhani, Caroline J. Finlayson, Susan A. Dilly, Mitesh Gandhi. Book Basic Pathology. Click here to navigate to parent product. Edition 5th Edition. First Published Imprint CRC Press. Pages eBook ISBN Vascular occlusions are common structural modifications made by many plant species in response to pathogen infection.

However, the functional role(s) of occlusions in host plant disease resistance/susceptibility remains controversial. This study focuses on vascular occlusions that form in stem secondary xylem of grapevines (Vitis vinifera) infected with Pierce’s disease ([PD][1]) and the.

We conclude that thrombin is the principal mediator of platelet-dependent hemostatic plug formation and of the formation of platelet-dependent high-flow acute graft thrombosis and occlusion. Moreover, FPRCH2Cl or other synthetic antithrombins may provide effective antithrombotic therapy for both arterial and venous thrombosis by simultaneously.

Blood flow restriction training (also abbreviated BFR training) or Occlusion Training is an exercise approach whereby resistance exercise or aerobic exercise is performed whilst an Occlusion Cuff is applied to proximal aspect of the muscle.

In this novel training method, limb (legs or arms) blood flow is restricted via the occlusion cuff throughout the contraction cycle and rest period. Joshua Broder MD, FACEP, in Diagnostic Imaging for the Emergency Physician, Acute Mesenteric Artery Occlusion. Acute mesenteric artery occlusion and ischemia can occur from in situ thrombosis or embolic events.

Atrial fibrillation is likely the most common cause, accounting for 95% of cases in one prospective study. 62 Dissection of mesenteric vessels can complicate aortic dissection or. Language: English ISBN: (cloth: alk. paper), (cloth: alk.

paper), (paper: alk. paper), (paper: alk. paper) LCCN: MeSH: Platelet Activation/physiology; Vascular Diseases/etiology* Publication Type(s): Congresses Notes: "Third International Meeting on Platelets and Vascular Occlusion. From the Boston University School of Medicine, Whitaker Cardiovascular Institute, Boston, Mass.

Hemostasis is a normal process preventing the sequelae of uncontrolled hemorrhage. In certain settings, these same processes cause adverse clinical events due to thrombotic occlusion of a vessel. The. FeCl 3 treatment of the inferior vena cava causes platelet-dependent stable thrombus formation.

Stable, occlusive thrombus formation can be induced in a murine carotid artery (CA) by treatment with FeCl 3 [9, 11, 12]. FeCl 3-induced stable thrombus formation in the CA is GPIbα-dependent and therefore platelet-dependent [9, 11, 12].

Manage as thrombotic occlusion if unable to determine type of occlusion. [IB] Promptly administer thrombolytic agents approved for restoring CVAD patency in catheter with partial, withdrawal, or complete occlusion suspected to be caused by blood/fibrin.

[IB] Treat all catheter lumens with partial, withdrawal, or complete occlusion. from those with retinal artery occlusion. The diagnostic criteria for this distinction included characteristic edema of the entire retina (central retinal artery occlusion) or a segment of the retina (branch occlusion) with evidence of interruption of blood flow in retinal arteries (e.g., "boxcarring") and a normal appearance of the optic disc.

This platelet-dependent thrombosis coupled with the potential for pulmonary vascular endothelial dysfunction (as suggested by the cremaster muscle vascular experiments) offers a ready explanation for the increased mortality in the GPx-3 (−/−) mice compared with the wild type mice.

Vascular occlusion in APS may involve arteries and veins at any level of the vascular tree and in all organ systems [1,24,40,41].Analysis of the children with aPL-related thrombosis included in the Ped-APS Registry revealed that 60% of pediatric APS patients presented with venous thrombosis, 32% with arterial thrombosis, 6% with small-vessel thrombosis, and 2% with mixed arterial and.

Retina Blood Vessel Occlusion. Retinal emboli are the most common associated finding in embolic retinal-vascular disease, and there are two main types seen in carotid disease: (1) cholesterol (Hollenhorst plaques), which have a refractile, metallic gold. Neutrophil aggregation is platelet-dependent.

Intestinal I/R injury is associated with platelet activation and formation of microvascular thrombi in the intestinal microcirculation (24, 25, 36). Depletion of platelets using an anti-GPIbβ antibody eliminated neutrophil aggregation induced by. Vascular occlusion is caused by an accidental injection of filler into an artery.

This results in a blockage of circulation in oxygen and nutrients to cells in the area. Experts concur that compression can also be a cause. NYC’s Dr. Doris Day admits that the topic of vascular occlusion is.

Dr Tim Pearce has been practicing medical aesthetics for over 10 years, and in Aprilhe experienced his first vascular occlusion when injecting the dermal filler.

This article has been taken from the A True Story: Emergency Reversal of Filler interview with Dr Adam Cheong on the Aesthetics Mastery podcast (found on iTunes and Soundcloud).

Glutathione peroxidase-3 (GPx-3), a member of the selenocysteine-containing GPx family, is a major antioxidant enzyme in plasma that scavenges reactive oxygen species (ROS) arising from normal metabolism or after oxidative insult, 1 thereby maintaining the vasorelaxant and antithrombotic properties of the vascular endothelium.

Of the 5 known GPx isoforms, GPx-3 is the only one found in the. The use of enzyme inhibitors to clarify the role of thromboxane A2 in vasoocclusive disease has been complicated by their non-specific action. To address this problem we have examined the effects of thromboxane A2/prostaglandin endoperoxide receptor antagonism in a canine model of platelet-dependent coronary occlusion.

Angiogram shows superficial femoral artery occlusion on one side (with reconstitution of suprageniculate popliteal artery) and superficial femoral artery stenosis on other side.

This is most common area for peripheral vascular disease. Peripheral arterial occlusive disease. Procedures performed during acute admission for peripheral arterial. Previous evidence has suggested that plasmin, in addition to its proteolytic action on fibrin, may affect platelet function.

To test the effects of plasmin generated in vivo by the thrombolytic agent streptokinase (SK) on platelet-dependent vascular occlusion, we have used a well-established canine model of experimental coronary artery stenosis which produces platelet aggregate-dependent.

This study examined the potential function of HO-1 in regulating platelet-dependent arterial thrombosis.

Platelet-rich thrombi were induced in C57BL/6J mice by applying 10% ferric chloride to the exposed carotid artery. Mean occlusion time of wild-type mice (n = 10) was ± min versus ± min for HO/-mice (n = 11, p = Central retinal artery occlusion is characterized by painless, acute vision loss in one eye.

Upon fundoscopic exam, one would expect to find: cherry-red spot (90%) (a morphologic description in which the normally red background of the choroid is sharply outlined by the swollen opaque retina in the central retina), retinal opacity in the posterior pole (58%), pallor (39%), retinal arterial.

Hayreh SS, Kolder HE, Weingeist TA. Central retinal artery occlusion and retinal tolerance time. Ophthalmology. Jan. 87(1) Hayreh SS, Jonas JB. Optic disk and retinal nerve fiber layer damage after transient central retinal artery occlusion: an experimental study in rhesus monkeys.

Am J Ophthalmol. Jun. (6) Ocular ischemic syndrome is the constellation of ocular signs and symptoms secondary to severe, chronic arterial hypoperfusion to the eye.

Amaurosis fugax is a form of acute vision loss caused by reduced blood flow to the eye; it may be a warning sign of an impending stroke, as both stroke and retinal artery occlusion can be caused by thromboembolism due to atherosclerosis elsewhere in the.

When an antagonist (L,) was administered at the time of occlusion in vehicle-treated dogs, coronary blood flow was restored. In vitro L, and a third antagonist, azaprostanoic acid, specifically reversed endoperoxide-induced platelet aggregation and vascular.

Vascular occlusion is a blockage of a blood vessel, usually with a differs from thrombosis in that it can be used to describe any form of blockage, not just one formed by a clot. When it occurs in a major vein, it can, in some cases, cause deep vein condition is also relatively common in the retina, and can cause partial or total loss of vision.

Symptoms of retinal vascular occlusion. The most obvious symptom of a retinal vascular occlusion is a sudden and drastic change in vision. The change can take a variety of forms such as blurry vision, partial or even complete loss of vision.

The changes in vision commonly only occur in one eye during a retinal vascular occlusion. Retinal vascular occlusion is a potentially serious condition, especially if hardening of the arteries, or atherosclerosis, already exists.

It most often occurs in middle-aged and older people. Carlo Patrono is the author of Radioimmunoassay in Basic & Clinical Pharmacology ( avg rating, 0 ratings, 0 reviews, published ), Platelets & Vasc.

Retinal artery occlusion, or eye stroke, can cause sudden and permanent vision loss. Learn about its causes, symptoms, and treatment. INTRODUCTION • Mesenteric vascular occlusion or mesenteric ischemia is a lethal condition resulting from critically reduced perfusion to the GIT.

• Despite advances in vascular surgery, it still remains a complex and disheartening disease with high mortality. • It account for % of admissions for abdominal pain.

Acute and long-term effects of resistance exercise combined with vascular occlusion on muscular function were investigated. Changes in integrated electromyogram with respect to time (iEMG), vascular resistive index, and plasma lactate concentration were measured in five men either during or after elbow flexion exercises with the proximal end of the arm occluded at 0– mmHg.

Vascular occlusion is a risk with dermal filler injections and can happen to experienced injectors as well as novices. However, you can significantly reduce your risk for this and other side effects by selecting a board-certified physician with extensive experience in dermal filler treatments.

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